The piggyBac™ transposon system is efficient for the production of recombinant protein expressing stable cell lines. Recent developments with piggyBac have achieved greater frequency of higher yielding cells and well as a 4-fold increase in protein production than traditional methods in CHO cells. Another advantage of the piggyBac system is its capability to stably deliver multiple transgenes simultaneously in a single transfection. Transposagen’s XTN™ TALEN technology for targeted gene modification provides improved production from genetics to large scale manufacturing of proteins.
Multi-subunit Cell Line Production
Current density recordings demonstrate the stability of PB-mediated functional protein multi-subunit protein expression. (Kahlig et al. PNAS (2010) 107 (4) 1343)
PIGGYBAC™ PARTNERING STRATEGY
Transposagen Biopharmaceuticals, Inc., holds worldwide exclusive rights for the use of piggyBacTM for almost all commercial applications, including human therapeutics. Custom services, research licenses and exclusive and nonexclusive commercial licenses are available through Transposagen. For more information please email info@transposagenbio.com or call 859-428-8561