Utilizing the FLASH™ high-throughput system. Transposagen can produce a site-specific nuclease targeting nearly any gene in any genome with the fastest delivery time in the industry. The XTN™ site-specific nucleases, also referred to as TALENs, permit researchers to specifically cut any DNA sequence, allowing for the creation of gene knockouts, knock-ins and single base pair edits. Researchers can now search Transposagen’s GENOME discovery database to choose any target. Transposagen will also perform custom animal model creation using the XTN™ technology.
REDUCED TIMELINES & AFFORDABLE GENE MODIFICATION
- Our licensed FLASH XTN™ TALEN production system improves efficiency and reduces timelines
- Site-specific genetic modification is now more affordable than ever
- Transposagen’s XTN™ TALENs are sequence verified and supplied in pre-tested expression vectors transfection ready for optimal efficiency
- Custom XTN™ TALENs are affordable and have absolutely no restrictions on use
- XTN™ TALENs are precise , reliable and guaranteed to bind and cut your gene of interest
CREATE GENETICALLY ENGINEERED CELLS, ANIMALS & PLANTS WITH EASE
Project Ready XTN™ TALENs Are Our Standard Section
Transposagen is an experienced XTN™ TALEN producer, in fact we use XTNs for complex and detail oriented projects such as custom genetically engineered rodents and cells lines. Our XTNs are the highest quality and activity in order to achieve consistent results for our customers.
Transposagen XTN™ TALEN Custom Service Programs
Transposagen has built-in value added for all of it custom programs designed to fit a wide range of research needs. The programs and pricing for custom XTN™ TALENs are described below.
All programs include: Custom target design is available free of charge but preferred to be done by the customer who is the expert in the gene target. Production and delivery of sequence verified, transfection ready XTN™ TALEN targeting the customers sequence of choice. For human, mouse, rat and zebrafish projects a control XTN™ targeting a gene with a known mutation frequency will be provided as well as a XTN™ targeting GFP as a control. This provides the customer with the ability to test a control along with the custom vectors for transfection or injection procedures.
Value™ Program $3,000 USD (price applies to US customers)
The value program is our standard most accessible service plan. We provide you with the fastest turnaround time in the industry, and high quality XTN™s so you can get on with your research. Program includes: custom XTN™ design, custom XTN™ production, delivery of sequence verified, transfection ready custom XTN
Guaranteed Success™ Program $4,000 (price applies to US customers)
Not all genomic targets are created equally. While most genes themselves are targetable, a small number of target sequences within a given gene are inaccessible by any site-specific nuclease due to chromatin structure and other factors. This is why we created the Guaranteed Success Program™ which allows you to purchase insurance on your XTN™. Program includes: custom XTN™ design, custom XTN™ production, delivery of sequence verified, transfection ready custom XTN™
If the first XTN™ does not cut your target you get a FREE rebuild If the second XTN™ does not cut you can purchase additional XTN™s for half price until success is achieved
Acceleration™ Program $5,000 (price applies to US customers)
Want to move your research further at an accelerated rate? Transposagen and its collaborators and customers have preliminary evidence demonstrating that by applying two XTN™s simultaneously targeting the same gene increases efficiencies. Program includes: 2 XTN™s targeting the same gene at different locations upfront at the time of the first order. If both XTN™s cut at low efficiency the customer has the option to purchase additional XTNs to the same target at half price of the Value™ Program until success is achieved.
We look forward to working with you and are always at your service: firstname.lastname@example.org
Download publications acknowledging Transposagen’s technology.
|Joung et al. (2012) Nature Biotech 30, 5||FLASH XTN assembly & Human Gene Targeting Efficiencies|
|Langenau et al. Plos One 2012-7-5-e37877||Zebrafish mutagenesis|
|Yeh et al. Nucleic Acids Research 2012 Vol 40 No 16||Zebrafish mutagenesis|
|Tesson et al. Nature biotechnology volume 29 number 8 august 2011||Rat mutagenesis|
|Hockemeyer et al. Nature Biotechnology volume 29 number 8 august 2011||Stem cell mutagenesis|
|Li et al. Nature Biotech. volume 30 number 5 may 2012||Plant mutagenesis|