Utilizing the FLASH™ high-throughput system. Transposagen can produce a site-specific nuclease targeting nearly any gene in any genome with the fastest delivery time in the industry. The XTN™ site-specific nucleases, also referred to as TALENs, permit researchers to specifically cut any DNA sequence, allowing for the creation of gene knockouts, knock-ins and single base pair edits. Researchers can now search Transposagen’s GENOME discovery database to choose any target. Transposagen will also perform custom animal model creation using the XTN™ technology.
REDUCED TIMELINES & AFFORDABLE GENE MODIFICATION
- Our licensed FLASH XTN™ TALEN production system improves efficiency and reduces timelines
- Site-specific genetic modification is now more affordable than ever
- Transposagen’s XTN™ TALENs are sequence verified and supplied in pre-tested expression vectors transfection ready for optimal efficiency
- Custom XTN™ TALENs are affordable and have absolutely no restrictions on use
- XTN™ TALENs are precise , reliable and guaranteed to bind and cut your gene of interest
CREATE GENETICALLY ENGINEERED CELLS, ANIMALS & PLANTS WITH EASE
Project Ready XTN™ TALENs Are Our Standard Section
Transposagen is an experienced XTN™ TALEN producer, in fact we use XTNs for complex and detail oriented projects such as custom genetically engineered rodents and cells lines. Our XTNs are the highest quality and activity in order to achieve consistent results for our customers.
Transposagen XTN™ TALEN Custom Service Programs
Transposagen has built-in value added for all of it custom programs designed to fit a wide range of research needs. The programs and pricing for custom XTN™ TALENs are described below.
All programs include: Custom target design is available free of charge but preferred to be done by the customer who is the expert in the gene target. Production and delivery of sequence verified, transfection ready XTN™ TALEN targeting the customers sequence of choice. For human, mouse, rat and zebrafish projects a control XTN™ targeting a gene with a known mutation frequency will be provided as well as a XTN™ targeting GFP as a control. This provides the customer with the ability to test a control along with the custom vectors for transfection or injection procedures.
We look forward to working with you and are always at your service: email@example.com
Download publications acknowledging Transposagen’s technology.
|Joung et al. (2012) Nature Biotech 30, 5||FLASH XTN assembly & Human Gene Targeting Efficiencies|
|Langenau et al. Plos One 2012-7-5-e37877||Zebrafish mutagenesis|
|Yeh et al. Nucleic Acids Research 2012 Vol 40 No 16||Zebrafish mutagenesis|
|Tesson et al. Nature biotechnology volume 29 number 8 august 2011||Rat mutagenesis|
|Hockemeyer et al. Nature Biotechnology volume 29 number 8 august 2011||Stem cell mutagenesis|
|Li et al. Nature Biotech. volume 30 number 5 may 2012||Plant mutagenesis|