piggyBac™ TRANSPOSON VECTORS
One of Transposagen’s exclusive genetic modification technologies is the piggyBac (PB) transposon. PB is a mobile genetic element that efficiently transposes between vectors and chromosomes via a “cut and paste” mechanism. The powerful activity of the PB system enables genes of interest in the PB vector to be easily mobilized into target genomes.
- Single transfection makes stable cell lines and animal models
- Effective in all mammalian genomes include human, rat and mouse
- No DNA cargo limit, integrate 1kb to over 100 kb
- Transgenic cell lines and animal model production
- Stem cell research: reprogramming, differentiation and selection
- RNAi: inducible and reversible knockdowns in cells and animal models
- Cell lines for robust protein production
- Cell and gene therapy
Transposagen provides a number of piggyBac vectors as off-the-shelf products as well as custom PB vector production services. PB vectors which were developed at Transposagen as well as investigator donated vectors are available.
Custom piggyBac Services:
- Custom vector production in as little as 2 weeks
- Custom gene editing vectors and HR donor vectors.
- Custom cell lines in as little as 8 weeks
CUSTOM piggyBac™ CELL: LINE & ANIMAL MODEL SERVICES
Transposagen’s capabilities don’t stop with vector construction. Ask about of custom piggyBac cell line and animal models services!