CUSTOM GENETICALLY MODIFIED RODENT MODELS
Transposagen has the industry’s most versatile collection of technologies for the production of genetically engineered rodents. These capabilities result in the most flexible and robust custom model generation services in the industry. The more targeted and complicated your therapeutics become, the more you need the right partner to advance your research. Working intimately with our scientific team will help you bring innovative solutions and products to market faster.
CUSTOM RAT MODELS AVAILABLE:
- Constitutive Knockout
- Conditional Knockout
- Knock-in
- Humanization
- Transgenic
- Inducible Transgenic
*BOTH INBRED AND OUTBRED RAT & MOUSE STRAINS AVAILABLE
PROGRAMS AND SERVICE
Our custom genetically modified rat services are provided on a milestone production and payment basis. The first milestone is vector construction. Transposagen will produce the vectors and send you the vector maps and sequences for verification along with the vectors, if requested. The second milestone is transfection, injection, selection and implantation. You will receive detailed reports demonstrating successful genetic modification of our stem cells. The third milestone is germline transmission and delivery of founders.
CUSTOM KNOCKOUT RATS AT HIGH EFFICIENCY
Atleast 5 genetically engineered founder rats from the very first litter when injecting custom XTN™ TALENs into rat embryos. Transposagen’s average founder production efficiency is over 20%