Accessible XTN™ TAL Effectors Now Commercially Available FLASH™ XTN™ TALE Nuclease technology, discussed in GEN shows incredible promise in producing “…high-precision and high-efficiency modifications in a target gene sequence to produce basic research tools and to enable dramatically improved gene therapy.” -Anton Simeonov (NIH) XTN™ TALE effectors empower you to edit, knockout or knock-in any sequence for genome editing, with applications in cells, [...]

The Lepob mouse strain has been used for decades to study obesity and diabetes, as well as for screening drugs. Transposagen’s Obese (OB) Rat™ now provides researchers with the advantage of the rat’s size and physiology on a leptin knockout background. The OB Rat™ carries a mutation (Q92X) which introduces a premature stop codon and [...]